
What Are Re-Inflators?
Re-inflators are an innovative category of injectable treatments that work differently from traditional fillers. Also known as biostimulators, these advanced products increase your own collagen and elastin production to gradually rebuild the structural support to where it used to be, leading to your more youthful appearance.
The primary biostimulator used at BelleSante is Sculptra, a poly-L-lactic acid (PLLA) formulation that serves as a catalyst for natural regeneration of our skin’s foundational structures. When strategically and expertly placed beneath the skin by our skilled injectors, this sophisticated product creates scaffolding that encourages your own cells to produce new collagen and elastin fibers. The result is a natural restoration of volume, as well as an improvement in skin texture that develops progressively over time, creating subtle yet significant improvements that our patients love.
Our approach to biostimulator treatments focuses on comprehensive facial rejuvenation, laying down a beautiful foundation to then be complemented with fine tuning with hyaluronic acid, for a very natural, never “done” look. By understanding the complex interplay between facial structure, skin quality and aesthetic balance, we create results that complement your unique features while restoring the architectural foundation that defines a youthful appearance.
Compared to Traditional Fillers That Simply Restore Lost Volume, Re-Inflators Offer Significant Advantages When Administered by Our Experienced Team
You are a good candidate for the use of re-inflators if you wish to:
- Experience gradual, progressive results that rejuvenate from within
- Achieve natural, beautiful-looking results with the creation of your own collagen and elastin for long-lasting results
- Re-establish your more youthful facial structure and foundational support
- Treat multiple areas or concerns for an overall more youthful look
- See subtle refinements, which leave you looking refreshed, not “done”
- Improve both foundational support and the texture of your skin, especially when combined with microneedling (See Exclusive BelleSante Radiant Refresh XO)

Your Treatment Experience at BelleSante
Your journey begins with a comprehensive expert consultation where we discuss your goals, assess your facial anatomy and evaluate, from the cellular level, how various factors — including volume loss, skin quality and your lifestyle — contribute to your concerns. This allows us to create a personalized treatment plan that addresses your needs while enhancing your authentic beauty.
Upon arrival for your treatment, you’ll be welcomed into a peaceful, spa-like environment where every detail has been designed with you in mind. Unlike traditional clinical settings, BelleSante offers a soothing atmosphere enhanced by gentle music, aromatherapy and other thoughtful touches to help you feel at ease. We also utilize a variety of comfort measures like “TAP-esthesia,” calming box breathing and roller balls for an anxiety-reducing experience. Patients feel calm and supported throughout their time with us.
Kristine Romine, MD or Sara Romine, DNP, FNP-C, will carefully analyze your facial anatomy to identify your optimal injection points. Then, using advanced injection techniques, we strategically place the biostimulator to restore structural support and enhance your facial contours. Many patients are surprised by how quick and comfortable the treatment process is and love the “halftime show,” looking in the mirror after one side of the face has been treated to see the difference!
Recovery & Results
After your biostimulator treatment, you can return to your daily activities immediately. For the best results, we do recommend avoiding excessive heat and alcohol for at least 48 hours. Some patients may experience mild swelling, redness, bruising or tenderness in treated areas that typically resolve within a few days. You can minimize the potential side effects by following our detailed aftercare instructions and advanced recovery protocols.
Unlike traditional fillers that provide immediate volume, re-inflators (biostimulators) work gradually. You will notice significant improvements initially, for the first 48 hours, from the sterile water used to carry the product to its destination in your skin, followed by a period where this initial volume diminishes. The true results begin to develop after four to six weeks as your body starts producing new collagen and elastin, with continued improvement for three to six months. After your treatment is complete, we always prepare you for the rest of your day by guiding you through application of your ideal personalized KRMD Skin Care regimen.
To maximize your results, you can pair your re-inflator/biostimulator (Sculptra) treatment with microneedling and the application of exosomes derived from day-zero stem cells to further stimulate collagen and elastin production to see incredible improvement in skin texture as well as fine lines. We call this signature treatment the BelleSante Radiant Refresh XO, an Exclusive option designed for highly motivated patients who want to look and feel their absolute best. Re-inflators/biostimulators are also optimally incorporated into your Exclusive BelleSante Skin Gym treatment plan — along with bespoke injectable hyaluronic acid (fine-tuning), paired with a neuromodulator every quarter and followed by your personalized at-home KRMD Advanced Medical Grade skincare “workout routine” allowing you to “Age in Reverse,” looking refreshed, vibrant, and always “Event Ready.”