The Science Behind Your Personal “Genetic Operating Manual”
Every cell in your body carries approximately 20,000 genes, however it's the variations in these genes — called Single Nucleotide Polymorphisms (SNPs) — that make you uniquely You! These genetic variations influence everything from how efficiently you absorb certain nutrients to your predisposition for inflammation, your response to different types of exercise, and even how quickly you metabolize caffeine.
Dr. Kristine Romine’s foundational background in internal medicine, combined with three decades of experience optimizing patient outcomes, brings deep clinical insight to our BioSculpt™ Wellness program. Both Kristine Romine, MD and Sara Romine, DNP, FNP-C, have completed intensive study through Genomics University, allowing them to interpret complex genetic patterns and create your practical, proactive, personalized BioSculpt™ Playbook to guide your daily habits.
Traditional medicine often takes a reactive approach, waiting for symptoms and disease to manifest before addressing health concerns. Our Functional Genomics counseling at BelleSante empowers You to be proactive — identifying potential challenges and opportunities before they manifest as health issues. This personalized precision wellness approach represents the ”Future of True Precision Healthcare” — one where your strategies are as unique as your fingerprint.
A Scientific Approach to a Lifetime of Wellness
At BelleSante by Kristine Romine, MD, we understand that true transformation requires more than generic medical advice or one-size-fits-all solutions. BioSculpt™ Wellness integrates interpretation of your own DNA via the leading, state-of-the-art, IntellxxDNA genomic technology and science-backed nutrition, vitamin, supplement, and lifestyle modification strategies to help you gain the knowledge you need to create a foundation for lasting vitality, all synthesized into your personalized BioSculpt™ Playbook
Through careful assessment of current health biomarkers, including baseline Biological Age Testing and one-time Genomic Analysis, Kristine Romine, MD and Sara Romine, DNP, FNP-C curate your “Personalized Prescribed Wellness” program which is conveyed through your Personal BioSculpt™ Playbook.
Your genetic analysis (what we call your “Operating Manual”) reveals insights across multiple health domains. Nutritional genomics shows us how your body processes different macronutrients, which vitamins you may need to supplement in higher doses if you don't carry the genes that code for the enzymes that enables your biology to utilize food or even the sun, in the case of Vitamin D metabolism, to make that vitamin, as well as reveal foods that may trigger inflammatory responses, due to your specific microbiome. Pharmacogenomics helps us understand how you metabolize medications, allowing for more precise dosing and fewer side effects. Exercise genomics reveals whether you're naturally built for endurance activities or power-based movements, helping optimize your fitness routine for maximum results.
Your Personalized Genomic Journey
Initial Consultation and Assessment
Your journey begins with a comprehensive consultation where we discuss your health history, current concerns, and wellness goals. During this session, Dr. Romine or Sara Romine, DNP, FNP-C, explains how our preferred genomic testing and subsequent Functional Genomics Counseling works to unveil your unique Single Nucleotide Polymorphisms and how the interplay of these SNPs will provide insights specifically relevant to your individual unique health and wellness journey. We also establish baseline health biomarkers through additional testing, including biological age assessment, to create a complete picture of your current health status.
This initial meeting allows us to understand not just what you hope to achieve, but why these goals matter to you. Whether you're seeking to optimize athletic performance, address chronic fatigue, prevent age-related diseases, or simply feel more energetic and vibrant, we tailor our approach to your unique aspirations. Understanding your Personal “Operating Manual” and aided by your BioSculpt ™ Playbook, our experts empower you to take control of your HealthSpan Optimization journey.
Your Genomic Testing Experience at BelleSante
Following your consultation, our team performs your IntellxxDNA genomic test for your convenience in the office. The process requires only a simple saliva sample, making it completely non-invasive and easy to complete in just a few minutes, after which our team will send your sample to the IntellxxDNA lab to be tested. Your sample is processed using advanced genomic sequencing technology that analyzes hundreds of genetic variants (SNPs) relevant to health and wellness.
The IntellxxDNA platform examines SNPs across multiple categories, including nutrient metabolism, detoxification pathways, inflammatory responses, cardiovascular health markers, and neurological function. This comprehensive analysis provides your unique, very detailed “Operating Manual” of your genetic predispositions, allowing us to identify both potential challenges and unique advantages encoded in your DNA.
Expert Analysis and Interpretation
Once your genomic results are received at BelleSante, our experts conduct a thorough review, interpreting the vast amount of information and synthesizing it into digestible, easy to navigate categories, adding to your BioSculpt™ Playbook at each consultation session. Dr. Romine or Sara Romine, DNP, FNP-C, can provide you with incredible insight into your personal genome and translate complex genetic information into practical, up to date, and clearly actionable strategies.
During each consultation, we walk through your robust genetic profile, starting with your highest priorities first, explaining what each finding means for your health and vitality. You'll discover which nutrients your body may have difficulty absorbing, learn about genetic factors that could influence your sleep patterns, and understand how your detoxification pathways function, and so much more. Most importantly, we provide solid, AI supported, evidence-based, well-researched intervention strategies, tailored specifically to your unique genetic makeup, that reveal a pathway to avert disease.
Personalized Protocol Development
Armed with insights from your genetic analysis, we develop comprehensive wellness protocols, that we call your Personalized BioSculpt™ Playbook, that addresses your unique opportunities for improvement and arms you with strategies to be successful. This isn't a generic supplement list or standard diet plan — it's a carefully crafted roadmap, based on the "cards in the hand you were dealt at birth." Your personalized protocol may include specific nutritional recommendations, targeted vitamin and supplement choices, lifestyle modifications, and even “Personalized Fitness Prescriptions” designed to work optimally with your genetic profile.
For example, if your analysis reveals genetic variations that affect folate metabolism, we might recommend specific forms of folate supplementation alongside foods rich in bioavailable folate. If you carry genetic markers associated with slower caffeine metabolism, we'll adjust recommendations around coffee consumption and timing to optimize your energy levels without disrupting sleep. If you don’t have the gene that codes for the enzyme that detoxes pollution, benzene, and pesticides, our experts will “prescribe” a supplement that accomplishes what your biology does not, resulting in a significant decrease in inflammation and reversal of “inflammaging.”
Ongoing Support and Optimization
Your genetic makeup never changes, but your needs and circumstances do. Through monthly counseling sessions with our experts, we guide you through implementing your personalized protocol and make adjustments based on your progress and feedback. Our Functional Genomics counseling always focuses on your specific areas of interest while ensuring you receive invaluable, otherwise unknown, information that represents a real health risk, and of course offer guidance and support throughout your wellness journey. If we uncover the need of pharmaceutical intervention or more intensive treatments, we offer a list of excellent physician experts to guide you in continued preventative healthcare.
Each monthly counseling session includes progress assessment, protocol refinements, and education about additional genetic insights that may become relevant as you advance in your wellness and preventative healthcare journey. This ongoing relationship ensures that your genomic insights continue to provide value and direction as your health goals elevate with your new found vitality and desire for healthy living.
Frequently Asked Questions
How accurate is genomic testing for health optimization?
IntellxxDNA testing analyzes well-researched genetic variants with established scientific literature supporting their health implications. While genetics represents approximately 25% of health outcomes (with lifestyle factors accounting for the remaining 75%), understanding your unique genetic predispositions (SNPs) allows for highly targeted interventions that can significantly impact your health and wellbeing.
Will my genetic information be kept private and secure?
Patient privacy and data security are paramount at BelleSante. Your genetic information is protected under strict confidentiality protocols, and we never share your data with third parties without explicit consent. IntellxxDNA also maintains rigorous security standards (identification by number only) to protect your genetic information.
How long does it take to receive results and develop my personalized protocol?
Most results are available within 2-4 weeks of sample collection. Following our expert review, we typically reach out to schedule your first consultation within one week of receiving your report. Your personalized protocol (BioSculpt™ Playbook) development begins immediately during this consultation.
Can genomic testing help with weight management?
Absolutely. Your genetic analysis reveals information about how your body processes carbohydrates, fats, and proteins, your satiety signals, and your metabolic tendencies. This information allows us to design nutrition and exercise protocols that work with your genetic makeup rather than against it.
