The BelleSante Radiant Refresh XO

The BelleSante Radiant Refresh XO Image

Restore Your Skin’s Natural Radiance from Within

When you look in the mirror, does your reflection match how youthful you feel inside? As we celebrate more birthdays, our skin gradually loses its natural volume and vitality, leading to changes that can affect our confidence. While individual treatments might temporarily mask these changes, they often fall short of creating the comprehensive renewal you desire.

At BelleSante by Kristine Romine, MD, we’ve pioneered an innovative approach that works with your body’s natural processes to restore your skin’s youthful vitality. The BelleSante Radiant Refresh XO combines powerful biostimulation with microneedling and advanced regenerative medicine to enhance your natural beauty from within, revealing the refreshed, radiant version of yourself from years past.

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What Is the BelleSante Radiant Refresh XO?

The BelleSante Radiant Refresh XO is a powerful and innovative cosmetic treatment protocol created by Kristine Romine, MD, that combines the use of a biostimulator (Sculptra) and microneedling with exosomes from day-zero stem cells to stimulate your own collagen production, improve volume loss and enhance the texture of your skin.

How It Works

Through decades of experience in “Partnering with Patients for a Lifetime of Healthy, Beautiful Skin™,” Dr. Romine has perfected the artful timing and combination of aesthetic treatments. Her innovative protocols maximize the benefits of each component while maintaining your comfort and minimizing downtime. Each element of the BelleSante Radiant Refresh XO is carefully curated and administered to create comprehensive results that look completely natural.

Treatment begins with the biostimulator Sculptra, a type of “re-inflator” made with poly-L-lactic acid, a synthetic material that triggers the production of our own collagen — an important protein that gives our skin structure and elasticity. As an injected biostimulator, it helps to restore very natural-looking volume over time, reducing the appearance of fine lines and wrinkles. We enhance these results with microneedling treatments that create tiny punctures in the dermis, activating the body’s healing response and further stimulating new collagen and elastin production, resulting in beautiful smoothness to the skin.

To complete your Radiant Refresh, we introduce exosomes derived from day-zero stem cells. 

Exosomes are small vesicles containing powerful growth factors, proteins, lipids, and other molecules from very young cells that help repair and regenerate tissue like very young cells. When administered by an expert, such as Dr. Romine or Sara Romine, DNP, FNP-C, exosomes work together to maximize your skin’s regenerative potential for truly remarkable results. 

Benefits of the BelleSante Radiant Refresh XO

  • Natural-looking volume restoration through your own collagen production
  • Enhanced skin regeneration with precisely timed application of exosomes
  • Gradual, progressive improvements over three to six months
  • Long-lasting results that can persist for up to two years when a full series of three to four sessions is completed; yearly session recommended for maintenance
  • Minimally invasive treatment with little to no downtime
  • Strategic treatment sequencing to maximize results
  • Personalized KRMD Advanced Medical Skin Care routine for optimal maintenance 

Recovery & Results

After the Treatment

You will receive your first massage and guided on technique, in office, directly after injections. At home, you will be asked to perform “5-5-5 massages” — 5 minute massages, 5 times a day, for 5 days to maximize results of optimal collagen and elastin tissue stimulation.

After your BelleSante Radiant Refresh XO treatment, you may experience mild redness and increased sensitivity that typically subsides within 24-48 hours. You will be absolutely delighted with your newfound youthful volume for the first 48 hours and we always encourage our Radiant Refresh lovers to plan a nice event for the first two days. Two days after the procedure, you will note the original volume is back to your baseline as the sterile water the biostimulator is mixed in has fully resorbed into your body. Don’t worry… the desired volume is on its way and will be enhanced by your adherence to the “5-5-5 massages.” Your results develop gradually as the treatments work with your body’s natural processes. While you may notice initial improvements in skin firmness and texture within the first few weeks, the most significant changes emerge over the following months as new collagen and elastin form. 

Dr. Romine and Sara Romine, DNP, FNP-C, provide comprehensive guidance throughout your treatment journey, including detailed instructions for maximizing your results with your prescribed KRMD Advanced Medical Skin Care routine. Their expertise ensures optimal outcomes while maintaining your comfort and safety at every step.

Ideal Candidates for the Bellesante Radiant Refresh XO

The BelleSante Radiant Refresh XO offers a sophisticated solution for those seeking the most natural-looking rejuvenation. This treatment excels at addressing the early signs of aging while promoting long-term skin health through enhanced collagen production.

You may be an ideal candidate for this BelleSante Exclusive Treatment if you:

  • Want to restore your skin’s natural radiance and vitality 
  • Notice early signs of volume loss or skin laxity 
  • Prefer gradual, natural-looking improvements 
  • Seek long-term results through collagen stimulation 
  • Value treatments that work with your body’s natural processes

During your consultation, Dr. Romine and Sara Romine, DNP, FNP-C, will evaluate your skin’s current condition and discuss how the BelleSante Radiant Refresh XO can be customized to address your specific concerns while supporting your long-term aesthetic goals.

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What Our Clients Are Saying

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“Just had The most amazing visit with Dr. Romine!!! She is so knowledgeable and caring. What I love most is her passion for health and the full picture! Exercise, eating right, hormones and so much more. She’s interested in the whole body. Once you find someone this good … you’re a client for life!!”

Tonya R.
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"I’m 69 years old. I experienced a package of six Emsella Chair treatments before taking a cruise vacation. I was very pleased to have experienced such a remarkable improvement. I was able to do all ports of call without worrying about finding a toilet! It was so freeing! Thank you, Dr. Romine."

Terri M.
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“Every aspect of my visit was above and beyond…Dr. Romine was just amazing. She answered all my questions and went through the procedure of Ellacor showing me pictures of how it works and before and after pictures of other patients that have had it done. She is the best example of how well you heal and look after having done it herself…I would highly recommend BelleSante.”

Stacy D.
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"Dr. Kristine Romine is the best! Upon my last visit she took her time and even spent a moment educating my daughters who were tagging along with me on the importance of skin care and sunscreen. Her office has the newest and often only technology in the industry. I couldn't imagine going anywhere else!"

Sarah W.
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"I was having at a minimum of two migraines a week. My peripheral vision would be blacked out, nausea would set in, I would have a sharp and throbbing pain in my forehead and occipital area, as well as sensitivity to noise. After receiving Jeuveau injections in my masseters, forehead, and occipital areas from Dr. Romine, I went from having multiple migraines per week to one migraine in the last eight weeks. I am so appreciative to Dr. Romine for helping me feel normal again and allowing me to resume my normal schedule."

S.T.
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"Integrative medicine, health, and beauty combined with Dr. Romine at the helm. It doesn’t get any better than this. The practice is welcoming and the staff are friendly."

Mima S.
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“Dr. Romine, Sara, and the team at BelleSante are absolutely wonderful. I’ve been seeing Dr. Romine and Sara for years now and trust them wholeheartedly to recommend treatments in line with my desire to age gracefully…From the expertise of the team to the welcoming atmosphere, every detail at BelleSante is carefully curated to provide an exceptional experience. I would absolutely recommend them to anyone seeking top-quality treatments delivered by the best in the field.”

Krista D.

The BelleSante Difference

At BelleSante by Kristine Romine, MD, we understand that true transformation goes beyond addressing a line here or a wrinkle there. As pioneers in Aesthetic medicine, we take a more comprehensive approach to beauty and wellness that considers the complete picture — how you look, feel and live.

Achieving your goals isn’t just about using the latest tools and technology. It’s about how they’re artfully combined to bring out the best in your skin. Like a skilled architect, Dr. Romine and Sara Romine, DNP, FNP-C understand that rejuvenating one area sometimes requires strengthening the foundation around it first. This allows us to achieve results that not only enhance your authentic appearance but inspire overall beauty and wellness, as well as confidence.

We’ve seen firsthand how looking and feeling your best can transform your mindset and improve all aspects of your life. Our patients often find that once they begin their aesthetic journey with our professionals, they feel empowered to pursue goals they once thought were out of reach. That is the true BelleSante difference: providing you with the knowledge and support you need to live your most vibrant life.

At BelleSante, we “Partner with our patients for a Lifetime of Beautiful Health.”

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Connect With Us

At BelleSante by Kristine Romine, MD, we believe in “Partnering with Patients for a Lifetime of Healthy, Beautiful Skin™.” Through our deep understanding of facial architecture and commitment to natural beauty, we help you achieve the refined, radiant results you deserve.

Ready to begin your transformation? Let’s create your personalized BelleSante Radiant Refresh XO treatment plan together.